eBioscience 13-5867-82 Biotin anti-mouse/human integrin beta7 100 ug

产品名称：Biotin anti-mouse/human integrin beta7 100 ug
产品货号：eBioscience 13-5867-82
产品规格：100ug
Anti-Human/Mouse Integrin beta 7 Biotin
Also known as: Integrin b7, ITGB7
Clone: FIB504
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-5867
Cat. No. Size
13-5867-80  25 ug 
13-5867-82  100 ug 
Description: The FIB504 monoclonal antibody reacts with human and mouse integrin β7. Integrin β7 is a 130 kD glycoprotein which associates with integrin α4 (CD49d) to form the α4β7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with αE (CD103) to form the αEβ7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin α4β7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin αEβ7 is E-cadherin (CD324). Integrin β7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
 

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