eBioscience 13-1529-82 anti-human CD152 Biotin 14D3 100 ug

产品名称：anti-human CD152 Biotin 14D3 100 ug
产品货号：eBioscience 13-1529-82
产品规格：100 ug
Anti-Human CD152 (CTLA-4) Biotin
Also known as: CTLA4
Clone: 14D3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-1529
Cat. No. Size
13-1529-82  100 ug 
Description: The 14D3 monoclonal antibody reacts with human CD152, also known as cytotoxic T lymphocyte antigen-4 (CTLA-4). CTLA-4, a protein with structural similarities to CD28, is expressed on activated T cells (activated B cells may also express CTLA-4) and binds the B7 family members, CD80 (B7-1) and CD86 (B7-2), with higher affinity than CD28 does. CTLA-4 and CD28 appear to deliver opposing signals to T cells: while CD28 is a potent costimulator, CTLA-4 restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. The cytoplasmic portion of CTLA-4 contains ER retention motifs, resulting in intracellular localization of a large proportion of newly synthesized CTLA-4 in response to TCR signaling.
 

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!