eBioscience 13-1060-81 anti-rat CD106 Biotin eBioMR106 (MR106) 50 ug

产品名称：anti-rat CD106 Biotin eBioMR106 (MR106) 50 ug
产品货号：eBioscience 13-1060-81
产品规格：50 ug
Anti-Rat CD106 (VCAM-1) Biotin
Also known as: VCAM1
Clone: eBioMR106 (MR106)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-1060
Cat. No. Size
13-1060-81  50 ug 
13-1060-82  100 ug 
13-1060-85  500 ug 
Description: The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
 

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