eBioscience 13-0689-82 anti-human CD68 Biotin eBioY1/82A (Y1/82A) 100 ug

产品名称：anti-human CD68 Biotin eBioY1/82A (Y1/82A) 100 ug
产品货号：eBioscience 13-0689-82
产品规格：100 ug
Anti-Human CD68 Biotin
Also known as: macrosialin
Clone: eBioY1/82A (Y1/82A)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-0689
Cat. No. Size
13-0689-80  25 ug 
13-0689-82  100 ug 
Description: The eBioY1/82 antibody reacts with CD68 which belongs to the sialomucin family and is closely related to the family of lysosomal-associated membrane proteins (lamps) and scavenger receptor. CD68 is predominantly an intracellular protein, found mainly in the late endosomal compartment but can be detected in smaller amounts on the surface of cells of mainly myeloid derived cells; monocytes and macrophages, dendritic cells (and in some langerhan cells), neutrophils, basophils mast cells, myeloid progenitor cells, and a subset of CD34+ hemopoietic bone marrow progenitor cells. The function has not been fully elucidated but based on it's homolgy and structure suggests a role in antigen processing or presentation and protection of the lysosomal membrane from hydrolytic enzymes. Reports have also seen expression in activated T cells, and about 40% of peripheral blood B-lymphocytes and 50% of all B-ALL.
Staining with eBioY1/82A shows surface staining on B cells and a minor percentage of monocytes while intracellular staining results in about 50% of B cells and most monocytes.
 

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