eBioscience 13-0661-80 anti-mouse CD66a (CEACAM, CEACAM1a) Biotin CC1 25 ug

产品名称：anti-mouse  CD66a (CEACAM, CEACAM1a) Biotin CC1 25 ug
产品货号：eBioscience 13-0661-80
产品规格：25 ug
Anti-Mouse CD66a (CEACAM1) Biotin
Also known as: CEACAM, BGP, biliary glycoprotein
Clone: CC1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-0661
Cat. No. Size
13-0661-80  25 ug 
13-0661-82  100 ug 
Description: The monoclonal antibody CC1 recognizes CD66a, also known as carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), biliary glycoprotein, and BPG. Expression of CD66a is found on brush borders, epithelial, and endothelial cells. In hematopoietic cells expression is found abundantly on B cells, as well as some NKs, monocytes, DCs, and granulocytes. Although low levels of mRNA have been identified in T cells in humans, resting mouse T lymphocytes are not reported to express CD66a, as confirmed by lack of staining with CC1 antibody. In humans, expression levels of CD66a have been used to identify malignancies. CD66a plays a key role as a regulator of BCR activation of B lymphocytes.
An alternate allele, CEACAM1b, is expressed in SJL mice; therefore, CC1 does not stain SJL tissue. The monoclonal CC1 has been shown to block viral infection and also enhance B cell proliferation when combined with IgM crosslinking.
 

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