eBioscience 13-0401-81 anti-mouse CD40 Biotin 1C10 50 ug

产品名称：anti-mouse CD40 Biotin 1C10 50 ug
产品货号：eBioscience 13-0401-81
产品规格：50 ug
Anti-Mouse CD40 Biotin
Also known as: TNFRSF5
Clone: 1C10
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-0401
Cat. No. Size
13-0401-81  50 ug 
13-0401-82  100 ug 
13-0401-85  500 ug 
13-0401-86  1 mg 
Description: The 1C10 monoclonal antibody reacts with mouse CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.
 

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