eBioscience 13-0252-81 anti-mouse CD25 Biotin eBio7D4 (7D4) 50 ug

产品名称：anti-mouse CD25 Biotin eBio7D4 (7D4) 50 ug
产品货号：eBioscience 13-0252-81
产品规格：50 ug
Anti-Mouse CD25 Biotin
Also known as: Interleukin-2 Receptor alpha
Clone: eBio7D4 (7D4)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-0252
Cat. No. Size
13-0252-81  50 ug 
13-0252-82  100 ug 
13-0252-85  500 ug 
13-0252-86  1 mg 
Description: The eBio7D4 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage, as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) followed by subsequent detection with another one. eBio7D4 has been reported to block IL-2 binding but can be overcome by additional IL-2. The monoclonal antibody PC61.5 (cat. 16-0251) is recommended for in vivo studies.
 

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