eBioscience 12-9179-42 Anti-Human IL-17AF (heterodimer) (clone 20LJS09) PE, 100

产品名称：Anti-Human IL-17AF (heterodimer) (clone 20LJS09) PE, 100 tests
产品货号：eBioscience 12-9179-42
产品规格：100 tests
Anti-Human IL-17AF PE
Also known as: Interleukin-17AF
Clone: 20LJS09
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-9179
Cat. No. Size
12-9179-41  25 tests 
12-9179-42  100 tests 
Description: The 20LJS09 monoclonal antibody reacts with human interleukin (IL)-17AF heterodimer. This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers. IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.
 

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