eBioscience 12-6691-80 Anti-Mouse Egr2 PE (erongr2) 25 ug

产品名称：Anti-Mouse Egr2 PE (erongr2) 25 ug
产品货号：eBioscience 12-6691-80
产品规格：25 ug
Anti-Mouse Egr2 PE
Also known as: Krox-20
Clone: erongr2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6691
Cat. No. Size
12-6691-80  25 ug 
12-6691-82  100 ug 
Description: This erongr2 monoclonal antibody recognizes mouse early growth response 2 (Egr2, Krox-20). Egr2 is a zinc finger-containing transcription factor that is important for the development of T cells and NKT cells. Egr2 is predominantly expressed in the thymus and nervous system, and it is also upregulated in T cells following TCR-crosslinking. Upregulation in all non-adherent mouse splenocytes has been observed following stimulation with phorbol 12-myristate 13-acetate (PMA) and ionomycin. Egr2 is believed to antagonize T cell activation and has also been reported to promote apoptosis. The erongr2 antibody also appears to modestly stain a subpopulation of T cells and B cells in freshly isolated spleen cells. The erongr2 monoclonal antibody is specific for Egr2 and does not crossreact to Egr3, based on immunoblot analysis.
 

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