eBioscience 12-6319-42 Anti-Human CD156c (ADAM10) (clone OV1F12) PE, 100 tests

产品名称：Anti-Human CD156c (ADAM10) (clone OV1F12) PE, 100 tests
产品货号：eBioscience 12-6319-42
产品规格：100 tests
Anti-Human CD156c (ADAM10) PE
Also known as: Disintegrin and metalloproteinase domain-containing protein 10
Clone: OV1F12
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6319
Cat. No. Size
12-6319-41  25 tests 
12-6319-42  100 tests 
Description: This OV1F12 (1F12HE) monoclonal antibody reacts with human CD156c, which is also known as a disintegrin and metalloproteinase domain-containing protein (ADAM) 10. This type I transmembrane glycoprotein is expressed ubiquitously on hematopoietic and non-hematopoietic cell types. Studies demonstrate that CD156c expression is regulated by PAX2 in cancer cells. CD156c plays a critical role in hematopoiesis, including lymphocyte development, and autoimmunity by regulating the shedding and secretion of various receptors and chemokines, including Notch, CD23, CXCL16, and the IL-6R. Finally, deregulated CD156c expression has been associated with T-cell acute lymphoblastic lymphoma (T-ALL) and Alzheimer’s disease.
 

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