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eBioscience 12-6238-42 Anti-Human CD263 PE (DJR3) 100 tests

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产品名称: eBioscience 12-6238-42 Anti-Human CD263 PE (DJR3) 100 tests
产品型号: 12-6238-42
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eBioscience 12-6238-42 Anti-Human CD263 PE (DJR3) 100 tests


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eBioscience 12-6238-42 Anti-Human CD263 PE (DJR3) 100 tests

产品名称:Anti-Human CD263 PE (DJR3) 100 tests
产品货号:eBioscience 12-6238-42
产品规格:100 tests
Anti-Human CD263 (TRAIL-R3) PE
Also known as: DcR1, TRAILR3, LIT, TRID
Clone: DJR3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6238
Cat. No. Size
12-6238-42  100 tests 
Description: The DJR3 monoclonal antibody reacts with human Decoy receptor 1 (DcR1), a glycophospholipid-anchored cell surface protein also known as TRAIL-R3, TRID, and LIT. DcR1 has an extracellular TRAIL binding domain and lacks the cytoplasmic death domain (DD) shared by several members of the TNF receptor superfamily. DcR1, along with DcR2, protects cells from TRAIL-mediated cytotoxicity. DcR1 binds to TRAIL and inhibits binding of TRAIL to DR4 or DR5. DcR1 is expressed broadly in many normal tissues at low level, but not in most tumors. Overexpression of DcR1 attenuates TRAIL-induced apoptosis.
 

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