eBioscience 12-6099-42 Anti-Human CX3CR1 (2A9-1) PE, 100 tests

产品名称：Anti-Human CX3CR1 (2A9-1) PE, 100 tests
产品货号：eBioscience 12-6099-42
产品规格：100 tests
Anti-Human CX3CR1 PE
Also known as: Chemokine C-X3-C receptor 1, V28
Clone: 2A9-1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6099
Cat. No. Size
12-6099-41  25 tests 
12-6099-42  100 tests 
Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.

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