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eBioscience 12-5956-80 anti-mouse BTLA / CD272 (Non-Blocking) PE 8F4 25 ug

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产品名称: eBioscience 12-5956-80 anti-mouse BTLA / CD272 (Non-Blocking) PE 8F4 25 ug
产品型号: 12-5956-80
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eBioscience 12-5956-80 anti-mouse BTLA / CD272 (Non-Blocking) PE 8F4 25 ug


eBioscience 12-5956-80 anti-mouse BTLA / CD272 (Non-Blocking) PE 8F4 25 ug  的详细介绍
eBioscience 12-5956-80 anti-mouse BTLA / CD272 (Non-Blocking) PE 8F4 25 ug

产品名称:anti-mouse BTLA / CD272 (Non-Blocking) PE 8F4 25 ug
产品货号:eBioscience 12-5956-80
产品规格:25 ug
Anti-Mouse CD254 (RANK Ligand) PE
Also known as: OPGL, TNFSF11, ODF
Clone: IK22/5
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-5952
Cat. No. Size
12-5952-81  50 ug 
12-5952-82  100 ug 
Description: The IK22/5 monoclonal antibody reacts with mouse TRANCE (TNF-related activation-induced cytokine receptor) also known as RANKL (receptor activator of NF-κB ligand) and OPGL (Osteoprotegerin Ligand). TRANCE is a type II membrane protein with predicted molecular weight of 35 kDa. Its extracellular domain is most closely related to TRAIL, FasL and TNF. TRANCE mRNA is upregulated by TCR stimulation and is expressed abundantly by mouse T cells not B cells in mouse thymus and lymph nodes. TRANCE-deficient mouse lacks osteoclasts. In addition, TRANCE has been shown to be involved in the interactions between T-dendritic and T-B cells. It was also found to be critical in osteoclast differentiation. The TRANCE-RANK interaction regulates the expression of the anti-apoptotic molecule Bcl-xL.
 

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