eBioscience 12-5846-82 PE Mouse/human TdT (clone 19-3), 100 ug

产品名称：PE Mouse/human TdT (clone 19-3), 100 ug
产品货号：eBioscience 12-5846-82
产品规格：100 ug
Anti-Human/Mouse TdT PE
Also known as: terminal deoxynucleotidyl transferase
Clone: 19-3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-5846
Cat. No. Size
12-5846-80  25 ug 
12-5846-82  100 ug 
Description: This 19-3 monoclonal antibody recognizes human and mouse terminal-deoxynucleotidyl transferase (TdT), a 60 kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. Tdt plays a critical role during TCR and Ig gene rearrangement. Regulation of expression in the mouse thymus correlates with T cell selection; decreased or absent after positive selection. Additionally Tdt has been shown to be present in lymphoma or lymphoblastic leukemia cells.
 

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