eBioscience 12-5230-82 Anti-Mouse MHC Class Ib (H2-M3) PE (mab 130) 100 ug

产品名称：Anti-Mouse MHC Class Ib (H2-M3) PE (mab 130) 100 ug
产品货号：eBioscience 12-5230-82
产品规格：100 ug
Anti-Mouse MHC Class Ib (H2-M3) PE
Also known as: MHC Ib, H2M3
Clone: mAb 130
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-5230
Cat. No. Size
12-5230-80  25 ug 
12-5230-82  100 ug 
Description: This mAb 130 monoclonal antibody reacts with mouse MHC class Ib H2-M3. This molecule specifically binds N-formylated peptides, which arise from mitochondrial or bacterial proteins. H2-M3-restricted T cells are mainly cytotoxic CD8+ T cells. H2-M3 associates with beta2-microglobulin. Finally, H2-M3 is expressed on cells in the spleen, Peyer’s patches, and lymph nodes, but not in the thymus. More specifically, cell surface expression of H2-M3 is low on B cells. However, H2-M3 can be induced by incubation with N-formylated peptide on T and B cells, macrophages, and dendritic cells.
 

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