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eBioscience 12-3391-82 PE Mouse Jagged-1 (clone HMJ1-29), 100 ug

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产品名称: eBioscience 12-3391-82 PE Mouse Jagged-1 (clone HMJ1-29), 100 ug
产品型号: 12-3391-82
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eBioscience 12-3391-82 PE Mouse Jagged-1 (clone HMJ1-29), 100 ug


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eBioscience 12-3391-82 PE Mouse Jagged-1 (clone HMJ1-29), 100 ug

产品名称:PE Mouse Jagged-1 (clone HMJ1-29), 100 ug
产品货号:eBioscience 12-3391-82
产品规格:100UG
Anti-Mouse CD339 (Jagged 1) PE
Also known as: JAG1, Jagged1
Clone: HMJ1-29
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-3391
Cat. No. Size
12-3391-80  25 ug 
12-3391-82  100 ug 
Description: This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen.
The HMJ1-29 antibody is reported to crossreact to rat.
 

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