eBioscience 12-3171-81 anti-mouse PDCA-1 (plasmacytoid DC Ag-1, pDC Ag-1, BST2,

产品名称：anti-mouse PDCA-1 (plasmacytoid DC Ag-1, pDC Ag-1, BST2, CD317) PE eBio129c (129c) 50 ug
产品货号：eBioscience 12-3171-81
产品规格：50 ug
Anti-Mouse CD317 (BST2, PDCA-1) PE
Also known as: plasmacytoid DC Ag-1, pDC Ag-1, BST 2, PDCA1
Clone: eBio129c (129c)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-3171
Cat. No. Size
12-3171-81  50 ug 
12-3171-82  100 ug 
Description: The eBio129c monoclonal antibody reacts with mouse PDCA-1 (BST2, CD317), a specific marker of plasmacytoid dendritic cells (pDC), also known as type I IFN-producing cells (IPC) in the naïve mouse. Mouse IPCs are typically CD11c+, CD11b-, B220+, Ly-6C+, and CD62L+. PDCA-1 is predominantly expressed by IPCs in the naïve mouse which represent sa very minor population (<0.5%) of splenocytes. It is upregulated on numerous cell types following stimulation which triggers an IFN response. PDCA-1 cycles between cell surface and intracellular compartments and may function to regulate trafficking of secreted cytokines. PDCA-1 (BST2) is the protein recognized by the antibody 120G8.
The epitope recognized by eBio129c is distinct from eBio927; thus, the antibodies can be used to costain, purify and identify pDCs.
 

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