eBioscience 12-1579-41 Anti-Human CD157 PE (SY11B5) 25 tests

产品名称：Anti-Human CD157 PE (SY11B5) 25 tests
产品货号：eBioscience 12-1579-41
产品规格：25 tests
Anti-Human CD157 PE
Also known as: BST-1, BP-3/IF-7
Clone: eBioSY11B5 (SY11B5)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1579
Cat. No. Size
12-1579-41  25 tests 
12-1579-42  100 tests 
Description: The eBioSY11B5 monoclonal antibody recognizes human CD157 (Mo5, BST-1). CD157 is a 42-45 kDa, GPI-anchored protein with structural and functional similarities with CD38. CD157 was initially cloned because of its expression on monocytes and macrophages, and was subsequently discovered to be the same protein named BST-1, discovered for its expression on bone marrow stromal cells and its ability to stimulate the proliferation of a mouse pre-B cell line. CD157 is a pleiotropic ectoenzyme and is thought to act independently as an enzyme and receptor. Similar to CD38, CD157 is involved in the metabolism of NAD+ and this activity may be involved in regulating intracellular Ca2+ levels. As a receptor, upon binding of its putative ligand, CD157 is thought to initiate a signal transduction cascade resulting in the phosphorylation of cytoplasmic proteins including focal adhesion kinase (FAK). The mechanism and functional significance of CD157-initiated signal transduction remain to be fully characterized.
 

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