eBioscience 12-1441-80 PE Mouse CD144 (clone BV13), 25 ug

产品名称：PE Mouse CD144 (clone BV13), 25 ug
产品货号：eBioscience 12-1441-80
产品规格：25 ug
Anti-Mouse CD144 (VE-Cadherin) PE
Also known as: Cdh5, Cadherin 5, Vascular endothelial cadherin
Clone: eBioBV13 (BV13)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1441
Cat. No. Size
12-1441-80  25 ug 
12-1441-82  100 ug 
Description: The eBioBV13 (BV13) monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.
 

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