eBioscience 12-1379-41 anti-human 4-1BB (CD137, 41BB, Ly-63, TNFRSF9) PE 4B4 (

产品名称：anti-human 4-1BB (CD137, 41BB, Ly-63, TNFRSF9) PE 4B4 (4B4-1) 25 tests
产品货号：eBioscience 12-1379-41
产品规格：25 tests
Anti-Human CD137 (4-1BB) PE
Also known as: 41BB, TNFRSF9, ILA
Clone: 4B4 (4B4-1)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1379
Cat. No. Size
12-1379-41  25 tests 
12-1379-42  100 tests 
Description: This 4B4 (4B4-1) monoclonal antibody reacts with human CD137 (also known as 4-1BB or TNFRSF9), which is an inducible member of the TNFR family of costimulatory molecules expressed on T cells, natural killer cells, dendritic cells, granulocytes, and mast cells. Involved in recruiting TNFR-associated factors (TRAF) 1 and 2, CD137 signaling plays a role in T cell activation, maintaining the survival of activated and CD8 memory T cells, as well as suppressing myelopoiesis and dendritic cell development. Stimulation of this receptor has also been shown to promote expansion of CD4+CD25+ T regulatory cells ex vivo. The ligand for CD137, 4-1BBL, is found on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
 

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