eBioscience 12-1303-42 Phycoerythrin (PE) Anti-human oncostatin M receptor (OSM

产品名称：Phycoerythrin (PE) Anti-human oncostatin M receptor (OSMR) 100 tests
产品货号：eBioscience 12-1303-42
产品规格：100 tests
Anti-Human Oncostatin M Receptor PE
Also known as: OSMR
Clone: AN-V2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1303
Cat. No. Size
12-1303-41  25 tests 
12-1303-42  100 tests 
Description: This monoclonal AN-V2 antibody reacts with the human oncostatin M (OSM) receptor. OSM, which belongs to the interleukin-6 cytokine family, is produced by T cells, activated monocytes, and dendritic cells. In humans, OSM can bind two unique receptor complexes. The type I OSM receptor is composed of the LIFR associated with gp130, and recognizes both LIF and OSM. The type II OSM receptor, which consists of gp130 and the OSMR subunit, specifically binds the cytokine, leading to activation of the JAK/STAT signaling pathway. Reports have also indicated a soluble form of the OSM receptor, which this antibody also recognizes. The OSM receptor is expressed in the bone marrow, endothelium, liver, lung, and numerous tumor cell lines.
The AN-V2 monoclonal antibody recognizes the type II (beta) OSM receptor.
 

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