eBioscience 12-1261-81 anti-mouse CD126 PE D7715A7 50 ug

产品名称：anti-mouse CD126 PE D7715A7 50 ug
产品货号：eBioscience 12-1261-81
产品规格：50 ug
Anti-Mouse CD126 PE
Also known as: Interleukin-6 Receptor alpha, IL-6Ra, Interleukin-6 receptor subunit alpha, IL-6R 1
Clone: D7715A7
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1261
Cat. No. Size
12-1261-80  25 ug 
Description: The monoclonal antibody D7715A7 recognizes mouse CD126, the IL-6 receptor α chain, a member of the Ig superfamily. CD126 can heterodimerize with CD130 (gp130) to form the high affinity IL-6 receptor. Once IL-6 is bound, signaling from the CD130 subunit is initiated and the receptor complex is internalized. The IL-6 receptor is also reported to exist as a soluble version, which bound to IL-6 acts in trans to signal. Expression is found on T lymphocytes in the periphery and during development in the thymus is restricted to SP populations, unlike gp130 which is expressed in all thymocytes. Additional expression has been shown on activated B lymphocytes, macrophages, granulocytes and CD34+ hematopoietic progenitor cells. The monoclonal antibody D7715A7 binding can be blocked addition of ligand (IL-6).
 

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!