eBioscience 12-1219-83 anti-mouse IL-21 Receptor PE eBio4A9 200 ug

产品名称：anti-mouse IL-21 Receptor PE eBio4A9 200 ug
产品货号：eBioscience 12-1219-83
产品规格：100 ug
Anti-Mouse IL-21 Receptor PE
Also known as: Interleukin-21 Receptor, IL-21R
Clone: eBio4A9
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1219
Cat. No. Size
12-1219-81  50 ug 
12-1219-83  200 ug 
12-1219-82  100 ug 
Description: The IL-21 receptor (IL-21R) combines with the common γ-chain to form a functional receptor for IL-21. IL-21R is expressed on several lineages including both resting and activated B, T, natural killer and dendritic cells. Binding of its ligand, IL-21, in these cells results in the activation of the Jak/Stat signal transduction pathway. The biological effects of ligand binding are diverse and depend on the cellular context and differentiation state of the cell. In the mouse, IL-21 binding to IL-21R induces the apoptosis of resting and activated B cells, enhances anti-CD3-mediated proliferation of T cells, and inhibits the maturation of dendritic cells and the IL-15-mediated expansion of NK cells.
 

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