eBioscience 12-1099-41 Anti-Human CD109 PE (HU17) 25 tests

产品名称：Anti-Human CD109 PE (HU17) 25 tests
产品货号：eBioscience 12-1099-41
产品规格：25 tests
Anti-Human CD109 PE
Also known as: CPAMD7, 150 kDa TGF-beta-1-binding protein
Clone: HU17
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1099
Cat. No. Size
12-1099-41  25 tests 
12-1099-42  100 tests 
Description: The HU17 monoclonal antibody reacts with human CD109, also known as the platelet-specific Gov antigen. CD109, a GPI-anchored monomeric glycoprotein, exists in two isoforms of 120 and 150 kDa, which are proteolytically degraded from a 170 kDa form. CD109 is expressed on activated T cells, activated platelets and endothelial cells. CD109 expression is also found on a subset of CD34+ cells in ***** and fetal bone marrow which contain megakaryocyte, myeloid, erythroid and multilineage progenitors, as well as pluriopotent hematopoietic stem cells. Recently, it has been demonstrated that CD109 is expressed on a variety of human cancer cell lines, and also lung and esophogeal cell carcinomas. In addition, CD109 was recently found to be a negative regulator of TGF-β in keratinocytes.
 

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