eBioscience 12-0431-83 anti-mouse CD43 PE eBioR2/60 200 ug

产品名称：anti-mouse CD43 PE eBioR2/60 200 ug
产品货号：eBioscience 12-0431-83
产品规格：200 ug
Anti-Mouse CD43 PE
Also known as: Leukosialin, LSN, Sialophorin, SPN, Ly-48
Clone: eBioR2/60
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-0431
Cat. No. Size
12-0431-82  100 ug 
12-0431-81  50 ug 
12-0431-83  200 ug 
Description: The eBioR2/60 monoclonal antibody reacts with mouse CD43, also known as leukosialin and sialophorin. CD43 has glycoforms of approximately 115 and 130 kDa, and is expressed by an early B cell subset in BM, thymocytes and mature T cells, NK cells, myeloid lineage cells and platelets. CD43 is reported to bind to CD54 and play a role in adhesion and B cell survival.
While the S7 and 1B11 monoclonal antibody clones detect only certain isoforms of CD43, data suggests that R2/60 detects the expression of both isoforms. It has been demonstrated that R2/60 stains the majority of CD4+ and CD8+ splenocytes, as well as a significant population of CD19+ splenocytes. However, the clones S7 and 1B11 stain only CD4+ and CD8+, or CD19+ splenocytes, respectively. This suggests that S7 and 1B11 recognize distinct epitopes which are differentially expressed by splenic B and T cells, whereas R2/60 recognizes an epitope shared by both isoforms of CD43.
 

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