anti-rat CD8b PE eBio341 (341) **

产品名称：anti-rat CD8b PE eBio341 (341) 100 ug
产品货号：eBioscience 12-0080-82
产品规格：100 ug
Anti-Rat CD8b PE
Also known as: CD8 beta, Ly-3
Clone: eBio341 (341)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-0080
12-0080-82  100 ug 
Description: The eBio341 monoclonal antibody reacts with rat CD8β. CD8β is a member of the immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8β expression is absent in athymic mice, which are populated by T-cells expressing CD8α homodimers. This has led to the idea that CD8β expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck. 
 

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