Anti-Helios (clone 22F6) FITC, 原装**

产品名称：Anti-Helios (clone 22F6) FITC, 100 ug
产品货号：eBioscience 11-9883-82
产品规格：10 ug
Anti-Helios FITC
Also known as: Ikaros family zinc finger 2, IKZF2
Clone: 22F6
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 11-9883
11-9883-80  25 ug    
11-9883-82  100 ug 
Description: This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and ***** mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia. 
 

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