anti-mouse Ly-49G2 FITC eBio4D11 (4D11) **

产品名称：anti-mouse Ly-49G2 FITC eBio4D11 (4D11) 50 ug
产品货号：eBioscience 11-5781-81
产品规格：50 ug
Anti-Mouse Ly-49G2 FITC
Also known as: LGL-1, Ly49G2, Ly49
Clone: eBio4D11 (4D11)
RUO: For Research Use Only. Not for use in diagnostic
procedures.
SKU# 11-5781
Cat. No. Size
11-5781-82  100 ug 
11-5781-81  50 ug 
11-5781-85  500 ug 
Description: The 4D11 monoclonal antibody reacts with Ly-49G2 (also known as LGL-1). The Ly-49 family of NK-cell receptors, members of the C-type lectin superfamily, are disulfide-linked type-II transmembrane protein homodimers with extracellular carbohydrate recognition domains, which bind to MHC class I alloantigens. The Ly-49 family members are expressed independently, such that an individual NK or T cell may display more than one class of Ly-49 receptor. Ly-49G2 is an inhibitory receptor expressed on subsets of natural killer (NK) cells, NK-T cells (in all strains tested), and on a population of memory CD8+ T cells (in C57BL/6 mice). The 4D11 antibody has been reported to cross react with the Ly-49AB6, Ly-49ABALB, and Ly-49T129/J inhibitory receptors and Ly-49LCBA/J activatingreceptors. The proportion of NK-T cells expressing Ly-49A and Ly-49G2 is higher in the thymus than in liver, and there is evidence that down-regulation of Ly-49 receptor expression is necessary for normal NK–T-cell development to occur. 
 

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!