anti-human CCR7 (CD197) FITC 3D12 25 tests **

产品名称：anti-human CCR7 (CD197) FITC 3D12 25 tests
产品货号：eBioscience 11-1979-41
产品规格：25 tests
Anti-Human CD197 (CCR7) FITC
Also known as: EBI-1, MIP-3 beta Receptor
Clone: 3D12
RUO: For Research Use Only. Not for use in diagnostic
procedures.
SKU# 11-1979
Cat. No. Size
11-1979-41  25 tests 
11-1979-42  100 tests 
Description: The 3D12 monoclonal antibody reacts with human CCR7, also known as EBI-1 and CD197. CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine), CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naïve from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC’s. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation. Expression of CCR7 on the cell surface can be down regulated upon ligand binding. 
 

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!