anti-mouse/rat CD49e (Integrin a5 chain, VLA-5A) FITC eBioHMa5-1 原装**

产品名称：anti-mouse/rat CD49e (Integrin a5 chain, VLA-5A) FITC eBioHMa5-1 (HMa5-1) 50 ug
产品货号：eBioscience 11-0493-81
产品规格：50 ug
Anti-Mouse/Rat CD49e (Integrin alpha 5) FITC
Also known as: Integrin a5, ITGA5, VLA5A
Clone: eBioHMa5-1 (HMa5-1)
RUO: For Research Use Only. Not for use in diagnostic
procedures.
SKU# 11-0493
Cat. No. Size
11-0493-81  50 ug 
11-0493-83  200 ug 
Description: The eBioHMα5-1 monoclonal antibody reacts with mouse and rat CD49e, also known as integrin α5 or VLA-5A. CD49e is a member of the integrin α chain family, and binds with CD29 (integrin β1) to form the receptor VLA-5, which binds the ligands fibronectin and fibrinogen. CD49e is a type I, single-pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells. In addition to its role in adhesion, VLA-5 contributes to T-cell co-stimulation. The eBioHMα5-1 monoclonal antibody has been demonstrated to interfere with VLA-5-mediated cell adhesion, and with the degranulation of IgE-sensitized rat RBL cells stimulated on fibronectin-coated plates. Furthermore, HMα5-1 injected into mice subcutaneously, along with anti-CD49d and anti-CD61, is able to inhibit passive cutaneous anaphylaxis. 
 

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!