anti-human CD47 FITC 2D3 25 tests **

产品名称：anti-human CD47 FITC 2D3 25 tests
产品货号：eBioscience 11-0478-71
产品规格：25 tests
Anti-Human CD47 FITC
Also known as: Integrin associated protein, IAP, neurophilin
Clone: 2D3
RUO: For Research Use Only. Not for use in diagnostic
procedures.
SKU# 11-0478
Cat. No. Size
11-0478-71  25 tests 
11-0478-73  100 tests 
Description: The monoclonal antibody 2D3 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small alternatively spliced cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with β3 integrins CD51/CD61 and CD41/CD61. Furthermore this interaction can mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages. CD47 is the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells. 
 

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