anti-rat CD3 FITC eBioG4.18 (G4.18) 50 ug**

产品名称：anti-rat CD3 FITC eBioG4.18 (G4.18) 50 ug
产品货号：eBioscience 11-0030-81
产品规格：50 ug
Anti-Rat CD3 FITC
Also known as: T3
Clone: eBioG4.18 (G4.18)
RUO: For Research Use Only. Not for use in diagnostic
procedures.
Cat. No. Size
11-0030-81  50 ug 
11-0030-82  100 ug 
11-0030-85  500 ug 
Description: The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.

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