Trichostatin A, Ready Made Solution 原装现货

产品名称：Trichostatin A
产品货号：sigma T1952
产品规格：200UL
Trichostatin A, Ready Made Solution
别名: TSA [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Biochem/physiol Actions
Trichostatin A (TSA) is a Streptomyces metabolite, which specifically inhibits mammalian histone deacetylase at a nanomolar concentration and causes accumulation of highly acetylated histone molecules in mammalian cells. For that reason, trichostatin A is a tool to study the consequences of histone acetylation in vivo.1 Trichostatin A induces cell differentiation, cell cycle arrest, reversal of transformed cells morphology, and apoptosis and is able to modulate transcription.2,3 TSA has been used to establish a new cloning technique, which increases the success rates for mouse cloning.4
Related Categories Antibiotic Ready Made Solutions, Antibiotics, Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, Cell Biology,
Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators, Epigenetics, Gene Regulation and Expression, Histone Deacetylase Inhibitors, Hydroxamic Acid Inhibitors, Molecular Biology, Reagents, T, Tools for Gene Regulation Research
更多... 
biological source：from Streptomyces sp. 
form：DMSO solution 
concentration：5 mM in DMSO (0.2 μm-filtered) 
shipped in：dry ice 

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