Arachidonic acid,ARA cis,花生四烯酸,花生油烯酸

Synonym:

cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid, Eicosa-5Z,8Z,11Z,14Z-tetraenoic acid

CAS Number:

506-32-1

Linear Formula:

CH₃(CH₂)₄(CH=CHCH₂)₄CH₂CH₂CO₂H

Molecular Weight:

304.47

Beilstein Registry Number:

1713889

EC Number:

208-033-4

MDL number:

MFCD00004417

PubChem Substance ID:

24846907

Biochem/physiol Actions

Arachidonic acid (AA) is an unsaturated ω⁶ fatty acid constituent of the phospholipids of cell membranes. Phospholipase A₂ releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via cytochrome p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, smooth muscle contraction, chemotaxis, cell proliferation and differentiation, and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.

Quality

Sigma-Aldrich will change the name of this product, eliminating the term "puriss." or "purum" beginning October, 2009. Please note that this is only a name change; the product qualities and specifications remain the same.

assay

>95.0% (GC)

refractive index

n20/D 1.4872(lit.)

bp

169-171 °C/0.15 mmHg(lit.)

mp

−49 °C(lit.)

density

0.922 g/mL at 25 °C(lit.)

shipped in

dry ice

storage temp.

−20°C

Personal Protective Equipment

Eyeshields, Faceshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US)

Risk Statements

19

WGK Germany

3

RTECS

CE6675000

Flash Point(F)

235 °F

Flash Point(C)

113 °C

品名

产地

货号

规格

单价

备注

花生四烯酸Arachidonic acid

Sigma

10931

250mg

询价

现货

花生四烯酸Arachidonic acid

Sigma

10931

1g

询价

现货