Doxorubicin≥98% (TLC),Doxorubicin hydrochloride,阿霉素,Doxorubicin HCL,Adriamycin

Synonym:

Adriamycin^® hydrochloride, DOX, Hydroxydaunorubicin hydrochloride

CAS Number:

25316-40-9

Linear Formula:

C₂₇H₂₉NO₁₁ · HCl

Molecular Weight:

579.98

Beilstein Registry Number:

4229251

EC Number:

246-818-3

MDL number:

MFCD00077757

PubChem Substance ID:

24893465

Frequently Asked Questions

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Biochem/physiol Actions

Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA;¹ Properties.^2,3

Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent; intercalates in DNA.

Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.

Legal Information

Adriamycin is a registered trademark of Farmitalia Carlo Erba S.R.L.

assay

≥98% (TLC)

mp

216 °C (dec.)(lit.)

storage temp.

2-8°C

Personal Protective Equipment

Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes

T

Risk Statements

45-22

Safety Statements

53-45

WGK Germany

3

RTECS

QI9295900

品名

产地

货号

规格

单价

备注

阿霉素 Doxorubicin

Sigma

D1515

10mg

询价

现货