BACE 1 ELISA

产品名称：BACE 1 ELISA
产    地：Demeditec 
产品货号：JP27752
产品规格：96 Tests
产品说明：
Special remarks: Neuropathologically Alzheimer's disease (AD) is characterized by widespread deposition of amyloid beta protein (Abeta) in the cerebral cortex, and since the intracerebral accumulation of Abeta is highly specific for AD and the gene mutation responsible for familial amyloidosis causes Abeta to increase, Abeta is thought to be of extremely great significance in the pathogenetic mechanism of AD. Abeta is generated by proteolysis of the Abeta precursor protein (APP), a type I membrane protein. The enzyme that cleaves it at the N-terminal is called beta secretase, and it is regarded as being the protease that acts at the initial step in the production of Abeta. The major beta secretase has been identified as beta-site APP Cleaving Enzyme 1 (BACE1), and BACE2 has been isolated as its homologue. Since increased BACE1 activity has also been reported in the brain of patients with sporadic AD, BACE1 inhibitors have been attracting attention as therapeutic agents for AD.
The kit can apply to assay of human, mouse and rat BACE1.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!