Tenascin-C Large (FNIII-C) ELISA

产品名称：Tenascin-C Large (FNIII-C) ELISA
产    地：Demeditec 
产品货号：JP27751
产品规格：96 Tests
产品说明：
Special remarks:  This test kit has been developped for the measurement of the Tenascin-C large variant including domain FNIII-C. There is also another testkit available for the measurement of the Tenascin-C large variant including domain FNIII-B (cat.-no. JP27767).
Tenascin-C is a modular and multifunctional extracellular matrix (ECM) glycoprotein that is exquisitely regulated during embryonic development and in ***** tissue remodeling.
In the ***** organism, reexpression of tenascin-C occurs in tumors and other pathologic conditions.  The precise function of the protein remains still unknown. Tenascin-C is a hexameric disulphide-linked protein with subunit molecular weights in the range of 210-400 kD.  It is primarily made up of 14.5 epidermal growth-factorlike repeat, 15 units similar to fibronectin type III-homology repeat and, at C-terminus, has a sequence with homology to the globular domain of the b and g chain of fibrinogen.  In addition, the amino-terminal -150 amino acids form an oligomerization domain allowing interaction of six subunits.  Different subunits are generated by alternative splicing of one common primary transcript.  Recent reports have suggested that tenascin-C is upregulated during oncogenesis, arthritis, liver, and lung fibrosis.  Increased serum levels have been reported in patients with cancer and liver diseases.
The IBL's human Tenascin-C High Molecular Weight Variants Assay kit (L) can  detect the non-spliced high molecular weight variants of tenascin-C including domain C in particular.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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