Thyreoidal Peroxidase-Ab (TPO-Ab)

产品名称：Thyreoidal Peroxidase-Ab (TPO-Ab)
产    地：Demeditec 
产品货号：DE03100
产品规格：100 Tests
产品说明：
Special remarks:
Autoimmune thyroid diseases encompass a wide spectrum of different clinical symptoms varying from hypo- to hyperthyroidsm (Hashimoto’s disease and Graves’ disease). The link between these extremes is the presence of serum auto-antibodies directed against the microsomal Antigen (TMAb) and/or thyroglobulin (TgAb). Thyroid autoimmunity is more frequently registered in women. Antibody prevalence in women increases with age, rising from approximately 10% at the age of 18-24 up to 30% at the age of 55-65 for TgAb and from 15% at the age of 18-24 up to 24% at the age of 55-65 for TMAb. These significant TgAb and TMAb titers can lead to the development of chronic thyroiditis, often resulting in hypothyroidism. Asymptomatic thyroid diseases with transient hyperthyroidism have been frequently noted in post-partum conditions. Subjects with moderate-sized goitres exhibit high TMAb and/or anti-TPO levels. A rise in TgAb, TMAb and/or anti-TPO has recently been proposed as an independent marker for “at-risk” pregnancies. In cases of primary myxoedema, significant TgAb and TMAb levels indicate the end stage of autoimmune atrophic chronic thyroiditis. In younger patients, a firm goitre found in combination with high TgAb and TMAb levels is generally a sign of Hashimoto’s disease, characterized by a progressive decrease in thyroid function leading to hypothyroidism. In Graves’ disease, the toxic goitre is associated to chronic thyroiditis, as confirmed by high TgAb and TMAb levels. Monitoring of TgAb, anti-TPO or TMAb levels is frequently used for treatment follow-up. TgAb can also be used as a marker for identification of family members exposed to the risk of transmission of autoimmune conditions.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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