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alpha-2,6-Sialyltransferase ELISA

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产品名称: alpha-2,6-Sialyltransferase ELISA
产品型号: JP27762
产品展商: 原装进口
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alpha-2,6-Sialyltransferase ELISA


alpha-2,6-Sialyltransferase ELISA  的详细介绍
alpha-2,6-Sialyltransferase ELISA

产品名称:alpha-2,6-Sialyltransferase ELISA
产    地:Demeditec 
产品货号:JP27762
产品规格:96 Tests
产品说明:
Special remarks: The antiserum in this assay also cross reacts with mouse and rat.
JP27762: recognizes the C-terminal and middle part of alpha-2,6-Sialyltransferase, common in human, rat and mouse. It can detect both of intact form and forms lacked N-terminal side parts.
The histopathological picture of Alzheimer's disease is characterized by senile plaques and neurofibrillary tangles, and because the senile plaques form first, they are considered the initial lesion. Senile plaques are known to be formed by accumulation of beta-amyloid peptide (Abeta). Abeta peptide is produced by the cleavage of amyloid precursor protein (APP) by two types of proteolytic enzymes. The first cleavage is performed by beta-secretase (BACE1), and the second gamma-secretase. It is thought that their inhibitors may be capable of serving as safe drugs for the treatment of Alzheimer's disease. In recent years a glycosyltransferase involved in the biosynthesis of sugar chains (alpha 2,6-sialyltransferase) has also been shown to be cleaved by BACE1. The cleavage site was identified at the same time, and as a result it was demonstrated that in rats it produces cleavage-type alpha 2,6-sialyltransferase (E41 Form). This product is a measurement kit that enables detection of human, rat and mouse alpha 2,6-sialyltransferase.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位,公司提供的产品涵盖了二十多个国家近五十万种产品,而且产品的数量与信息在不断的增长和更新,公司提供的产品能够使生命科学工作者加快对生物化学,分子生物学,细胞生物学以及蛋白质组学研究的认知,以及分子诊断和临床医学领域的应用。

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