N-ERC/Mesothelin mouse ELISA

产品名称：N-ERC/Mesothelin mouse ELISA
产    地：Demeditec 
产品货号：JP27783
产品规格：96 Tests
产品说明：
Special remarks:
INTRODUCTION
Erc has been identified as a gene showing stronger expression in cancer-affected renal tissue than in normal renal tissue in Eker rats (a rat model of renal cancer).
The  human  homologue  of  the  protein  encoded  by  this  gene  is  called  MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in  the  development  of  mesothelioma,  making  it  a promising  tumor  marker.  In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type  membranous  protein (about  71  kDa  in  molecular  weight),  which  is thought to be digested by a furin-like protease to yield fragments about 31 kDa and 40 kDa in size.
We think it is helpful for research of ERC/Mesothelin protein and have characterized the 31 kDa fragment as N-ERC/Mesothelin and the 40 kDa fragment as C-ERC/Mesothelin. This ELISA kit can measure Mouse N-ERC/Mesothelin.
PRINCIPLE
This kit is a solid phase sandwich ELISA using 2 kinds of highly specific antibodies. Tetra  Methyl  Benzidine  (TMB)  is  used  as  a  coloring  agent  (Chromogen).  The strength of coloring is proportional to the quantities of Mouse N-ERC/Mesothellin.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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