FSME (TBEV) IgG ELISA

产品名称：FSME (TBEV) IgG ELISA
产    地：Demeditec 
产品货号：DEFSM01
产品规格：96 Tests
产品说明：
Special remarks:
The DEMEDITEC TBEV IgG Antibody ELISA Test Kit has been designed for the the detection and the quantitative determination of specific IgG antibodies against TBEV in serum and plasma.
The infection with TBEV (tick-borne encephalitis virus) occurs predominantly in early summer through the bite of a tick, infected with TBEV. Ticks can become infected during any stage of their metamorphosis and transmit the virus diaplacentally. It is assumed that the virus hibernates in the tick or other vertebrates like porcupines, dormice, bats and deer. The incubation time ranges from 4 - 21 days. The viruses were earlier called arboviruses (arthropod-borne viruses) and are combined by their function into a group of infectious pathogens, being trans­mitted between vertebrates by the bite of blood-sucking arthropods. These viruses replicate in the organs of the receiving arthropods, without causing symptoms of a disease or tissue damage. The cyclus vertebrate-arthropod-ver­tebrate is kept alive by this vector which becomes life-long infectious through the blood-sucking of a vertebrate in the viraemic phase. Today, TBEV is allo­cated to the group of flaviviruses. Serologically, TBEV belongs to flavivirus group B. The pathogens consist of a single strand RNA and are inactivated by ether and sodium desoxycholate. The virus can be multiplied in the brain of newborn mice, but also in cell cultures (BHK-21 and Vero cells). The viral replication takes place in the cytoplasma of infected cells. The virions form in the Golgi region. The particle size of the viruses is 80 - 100 nm. The viruses are transmitted by the tick Ixodes ricinus. Characteristic for the disease is an involvement of the bulbary or cervical sec­tions of the spinal marrow as well as the development of ascending paralysis or hemiparesis. The occurence of residual paraplegia after the infection is not un­common. Typical infections show a two-stage course of the disease: the first phase comes along with an uncharacteristic feverish infect with strong head­aches,  the second phase with a meningo-encephalitis with or without pareses. After an incubation time of 3 - 28 days (depending on the dosis of the infec­tion), the initial phase develops with unspecific grippal symptoms. 3 - 7 days later, the symptoms decrease or, in approximately 10% of the cases, the sec­ond stage of the disease develops, marked by a renewed increase of tempera­ture, headache, pain in the limbs and meningo-encephalitic symptoms. Paraly­sis in the scapular area may occur. A few days later, a stage of improvement starts which generally lasts 1 - 3 weeks. If the CNS is involved, residual damage occurs in about 7% of the cases, letality is around 1%. The clinical picture of TBEV is uncharacteristic, thus, a serological laboratory diagnosis is required. The diagnosis of a fresh infection is done by the detec­tion of specific IgM antibodies.
TBEV-specific IgG antibodies are determined for two reasons:
a.) to monitor the course of the disease after infection with the TBEV (significant titer changes)
b.) to determine the „immune status“ after an „active immunization“ (vaccination protection)
The enzyme immunoassay for the detection of TBEV is highly sensitive and al­lows the determination of TBEV-specific antibodies in patient sera.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!