EBV (EBNA-1) IgG ELISA

产品名称：EBV (EBNA-1) IgG ELISA
产    地：Demeditec 
产品货号：DEEBN01
产品规格：96 Tests
其它产品：
EBV (EBNA-1) IgA Demeditec DEEBN02 96 Tests 1628
EBV (EBNA-1) IgM Demeditec DEEBN03 96 Tests 1628
产品说明：
Special remarks: The DEMEDITEC EBV EBNA-1 IgG Antibody ELISA Test Kit has been designed for the the detection and the quantitative determination of specific IgG antibodies against EBV EBNA-1 in serum and plasma.
The antigen used for coating the plöates is a recombinant one (sf-9, baculovirus).
In 1961 an infectious disease was identified in Uganda, which was correlated with the appearance of a defined type of tumor with children. The illness, which is found predominantly in Africa and Papua-New Guinea, was named Burkitt lymphoma from its discoverer. The Epstein Barr virus is made responsible for a variety of diseases like infectious mononucleosis, Burkitt lymphoma, as well as nasopharyngeal carcinoma. In addition, a role of the virus is discussed in connection with Hodgkin´s disease. Especially with teenagers there appears a glandular fever syndrome, which is called „kissing disease“. Diseases which are caused by the Epstein Barr virus are found mainly in persons with reduced im­munity. For example, the virus is associated with a lympho­proliferative disease which occurs after transplantation. The immune system of such patients is usually impaired by drug therapy. Also in immune-deficient AIDS patients, there appears frequently a state where cells at the rim of the tongue are infected (oral hairy leukoplakia). Infected persons keep the Epstein-Barr virus forever in their body, they are however mostly not ill. In the developing countries practically all the people are infected, in the western world the incidence is between 80% and 90%. The transmittance occurs already during childhood, perhaps by transfer from the mother, mainly via the saliva. During the active phase of the viral cycle, the Epstein-Barr virus produces about 100 different anti­gens, in the inactive phase around 10. The latter comprises among others the EBV nuclear antigen EBNA-1, which is closely correlated with a past infection and an immunity. The early antigen (EA) as well as the virus capsid antigen (VCA) from the active phase are also used as diagnostic markers. In a fresh infection, IgM antibodies against VCA and EA are determined by immunofluorescence or ELISA. Later VCA IgG and afterwards EBNA-1 IgG antibodies appear. The simultaneous activa­tion of VCA IgM and EBNA-1 IgG indicates correspondingly a reactivation of a latent EBV infec­tion. The Demeditec EBNA-1 IgG ELISA monitors a past infection satisfactorily and can be utilized for the as­sessment of blood samples before transfusions or transplantations and the exclusion of transmit­tance between children.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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