Aspergillus fumigatus IgG ELISA

产品名称：Aspergillus fumigatus IgG ELISA
产    地：Demeditec 
产品货号：DEASP01
产品规格：96 Tests
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产品说明：
Special remarks: The DEMEDITEC Aspergillus fumigatus IgG Antibody ELISA Test Kit has been designed for the detection and the quantitative determination of specific IgG antibodies against Aspergillus fumigatus in serum and plasma.
The antigen used for coating the microtiter plates is somatic + metabolic, CBS 545.65.
Aspergillus species of known pathogenicity to man are Aspergillus fumigatus, A. flavus, A. niger, A. terreus and A. nidulans. The most common pathogen of this genus is A. fumingatus which occurs in hay, grain, rotten plants and birds faeces. The main opportunistic invasive fungial infections are the candidal mycosis followed by aspergillosis. Generally infections with Aspergillus spp. are airborne.
Because of the ubiquity of Aspergillus species it renders more difficult to decide between contamination by commensals or a serious infection. Usually infection in man occurs in already damaged tissues only. Aspergillus spp. can cause a chronical infection of paranasal sinus, eyes or lungs.
Three types of lung-aspergillosis can be distinguished:
a: Acute infection (bronchial pneumonia; pneumonia)
Aspergillus pneumonia is mostly found in patients with neutropenia (decrease of neutrophil granulocytes), after a long-time therapy with glucocorticoids, in immunosuppressed patients (after organ transplantation) and in alcoholics.
b: Saprophytic aspergillom (compact reticulum of hyphae in the lungs)
Preformed caves in the lung due to a previous tuberculosis give place to a colonisation of Aspergillus species.
c: Allergic bronchopulmonal aspergillosis
This clinical picture is not due to an infectious disease but a hypersensitive reaction of the bronchial system (mediated by IgE) after inhalation of aspergillus spores. Subsequently the bronchial system produces highly viscous secretions, that may block the bronchial lumen. The patient develops difficulties of breathing and a fibrosis.
Next to ELISA the indirect Aspergillus hemagglutination test (Aspergillus HAT) can be performed to detect specific IgG and IgM antibodies. The HAT is not suitable as a screening test, however, because of its low sensitivity. In some high-risk patients it shows only low antibody titers. For a better diagnosis of invasive aspergillosis the brain or lung of these patients should be examined by a biopsy.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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