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CYFRA 21-1 ELISA

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产品名称: CYFRA 21-1 ELISA
产品型号: DE5070
产品展商: 原装进口
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CYFRA 21-1 ELISA


CYFRA 21-1 ELISA  的详细介绍
CYFRA 21-1 ELISA

产品名称:CYFRA 21-1 ELISA
产    地:Demeditec 
产品货号:DE5070
产品规格:96 Tests
产品说明:
Special remarks:
PRINCIPLE OF THE TEST
The DEMEDITEC CYFRA 21-1 ELISA Kit is a solid phase enzyme-linked immunosorbent assay (ELISA) based on the sandwich principle.
The microtiter wells are coated with a monoclonal [mouse] antibody directed towards a unique antigenic site of the CYFRA21-1 molecule.
An aliquot of patient sample containing endogenous CYFRA21-1  is incubated in the coated well with enzyme conjugate, which is an anti- CYFRA21-1  monoclonal antibody conjugated with horseradish peroxidase. After incubation the unbound conjugate is washed off.
The amount of bound peroxidase is proportional to the concentration of CYFRA21-1 in the sample.
Having added the substrate solution, the intensity of colour developed is proportional to the concentration of CYFRA21-1 in the patient sample.
Summary and Explanation
CYFRA 21-1 is a fragment of cytokeratin 19. Although expressed in all body tissues its major occurrence is in the lung, particulary in lung cancer tissues. The major diagnostic importance of CYFRA 21-1 as a tumor marker is in differential diagnosis, prognosis, and aftercare of non-small-cell lung cancer (NSCLC) patients.
Additionally, CYFRA 21-1 has been described as a tumor marker for the monitoring of bladder cancer.  
The CYFRA 21-1 ELISA uses the two mouse monoclonal antibodies KS19.1 and BM19.21 to determine cytokeratin 19 fragments.
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