SHBG IRMA

产品名称：SHBG IRMA
产    地：Demeditec 
产品货号：DE46100
产品规格：100 Tests
产品说明：
Special remarks:
Sex hormone-binding globulin (SHBG), also known as Testosterone-estradiol binding globulin (TEBG) and sex steroid binding protein (SBP), is a circulating glycoprotein with a molecular weight of around 86000. It is thought to be synthesized in the liver, and in the circulation its biological function is the transport of sex steroid hormones.It has a high binding affinity for testosterone, dihydrotestosterone and estradiol. Serum SHBG levels are relatively low at birth, increase to high levels during infancy, then decrease during puberty. The highest physiologic levels of SHBG are observed in pregnant, near-term maternal serum. Abnormal serum SHBG levels have been reported in number of conditions, including obesity and female hyperandrogenism (including polycystic ovary dicease). Serum SHBG levels are inversely related to free, presumably bioactive, testosterone concentracions, a “free testosterone index” based on the ratio of total testosterone to SHBG has been characterized.
In general the measurement of SHBG offers the possibility for calculating the free fraction of vatious steroid hormones based on the measurement of the total concentration in serum. But there is also a method available for the direct measurement of free steroid hormones in saliva. The metabolic activity of any steroid in any case is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering a group of different testkits in ELISA format for the measurement of free steroid hormones in saliva (please check in the chapter "saliva testing").
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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