AFP IRMA

产品名称：AFP IRMA
产    地：Demeditec 
产品货号：DE33100
产品规格：100 Tests
产品说明：
Special remarks:
DESCRIPTION
The 125I-AFP  IRMA  system  provides  direct  quantitative  in  vitro determination  of  human  alpha-fetoprotein (AFP) in human serum. AFP can be assayed in the range of 0-500 IU/ml using 50 µl serum samples.
INTRODUCTION
Alpha-fetoprotein (AFP) is a glycoprotein with a molecular mass of 65000. It is normally produced in large  amounts  by  the  fetal  liver.  AFP  level  increases  progressively  and  reaches  a  peak  at  the  30th week in the maternal serum, thereafter, it decreases gradually.  An  elevated maternal serum AFP is associated with neural tube defect (spina bifida) and placental abnormalities, whereas the decreased AFP levels in both maternal serum and amniotic fluid are related to fetal chromosomal abnormalities.
Patients  affected  by  liver  carcinoma,  testicular  or  ovarian  teratocarcinoma  commonly  present  high AFP levels. Although less frequently, an increased AFP concentration may also be observed in hepatitis, gastric, breast and bronchial tumors.
This kit can  be used in the risk assessment  of Down’s Syndrome (Trisomy 21) in combination with other biochemical and ultrasound parameters as specified above, taking also into account other data like maternal age and weight and using a validated software for Down’s Syndrome risk assessment:
Triple test: maternal serum AFP, hCG and unconjugated Estriol determination in the second trimester of pregnancy.
Quadruple test: maternal serum AFP, hCG, unconjugated Estriol and Inhibin-A determination in the second trimester of pregnancy.
Integrated test: maternal serum PAPP-A determination and nuchal translucency (NT) thickness measurement by an ultrasound scan in the first trimester of pregnancy and maternal serum AFP, hCG, unconjugated Estriol and Inhibin-A determination in the second trimester.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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