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Testosterone, free RIA

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产品名称: Testosterone, free RIA
产品型号: DE4369
产品展商: 原装进口
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Testosterone, free RIA


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Testosterone, free RIA

产品名称:Testosterone, free RIA
产    地:Demeditec
产品货号:DE4369
产品规格:96 Tests
产品说明:
Special remarks:
For IN VITRO determination of Free Testosterone (FT) levels in hirsutism and hypogonadism. Free testosterone diffuses through cell membranes and binds to specific receptor proteins (androgen receptors); the Testosterone-receptor complexes act as transcriptional modulators on cis-regulatory regions of many genes. Excess of Androgens in women causes hirsutism and signs of virilization; Testosterone level in serum has to be determined before and after ovarian and adrenal stimulation and supression to identify the source of excessive hormone production. Primary and secondary hypogonadism in men result in clinical hypoandrogenization, correlated with the degree of gonadal failure in Testosterone production.  The determination of serum Testosterone together with that of LH allows the correct assessement of those conditions. The diagnosis of true anorchia also requires to discriminate this condition from cryptorchidism.  Under prolonged hCG stimulation, Testosterone levels remain very low in true anorchia while cryptorchid testes can respond to stimulation. Androgen resistance syndromes, due to X linked androgen receptor gene deficiencies, are made of various degrees of sexual ambiguity.  Whatever the severity of the phenotypical abnormalities, serum Testosterone is systematically high in regards to elevated LH serum levels in these conditions. Testosterone assays include total testosterone (direct, extraction, coated tubes) and free testosterone determinations. Total Testosterone in plasma includes free Testosterone and Testosterone bound to SHBG, albumin, CBG. The mean percentage of each in normal men is 2.7, 32, 65 and <0.1 respectively. Solvents break the protein binding in extraction assays whereas blocking agents release Testosterone from proteins in direct assays. The advantage of a free testosterone assay is that free testosterone concentrations are in equilibrium with testosterone bound to receptors in the organs.
There is an alternative method available for the measurement of free Testosterone in saliva. This non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering such a testkit in ELISA format with the catalogue number DES6622.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位,公司提供的产品涵盖了二十多个国家近五十万种产品,而且产品的数量与信息在不断的增长和更新,公司提供的产品能够使生命科学工作者加快对生物化学,分子生物学,细胞生物学以及蛋白质组学研究的认知,以及分子诊断和临床医学领域的应用。

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