CA 19-9 IRMA

产品名称：CA 19-9 IRMA
产    地：Demeditec 
产品货号：DE4046
产品规格：96 Tests
产品说明：
Special remarks:
CLINICAL BACKGROUND
CA 19-9, equivalent to Sialyl Lewis antigen, is a mucin type glycoprotein found in the blood repetitively bearing a carbohydrate epitope which is specifically recognized by the mouse monoclonal antibody, C192. CA 19-9 is an oncofetal antigen, expressed by several different cancers, but especially carcinomas of the gastrointestinal tract. It is present in the fetal epithelium of the stomach, intestine, liver and pancreas. CA 19-9 is a tumor marker for pancreatic, gallbladder, gastric and colorectal cancers. CA 19-9 can be used to track treatment progress of previously diagnosed cancer. This blood test in conjunction with periodic CT scans will show whether the cancer is in remission or is continuing to grow. However, it is more useful in measuring the effectiveness of cancer treatment by studying the patient’s CA 19-9 levels over time. There are benign diseases of the bile ducts and pancreas that occasionally result in elevated CA 19-9 levels and a low CA 19-9 level does not exclude the possible presence of a malignant tumor. For this reason, the determination of CA 19-9 concentrations is not considered as a diagnostic test.
PRINCIPLES OF THE METHOD
The Demeditec CA 19-9-IRMA is a two-step immunoradiometric assay based on coated?tube separation. Mab1, the capture antibody, is attached to the lower and inner surface of the plastic tube. Add calibrators or samples to the tubes. After incubation, washing removes the occasional excess of antigen. Addition of Mab2, the signal antibody labelled with 125I, will complete the system and trigger the immunological reaction. After washing, the remaining radioactivity bound to the tube reflects the antigen concentration.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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