hGH

产品名称：hGH ELISA
产    地：Demeditec 
产品货号：DE3552
产品规格：96 Tests
产品说明：
Special remarks:
hGH is a polypeptide hormone (molecular weight 21,500 Da) produced by the acidophil cells of the anterior pituitary under the control of two main substances from the median eminence : Growth-hormone Releasing Factor (GRF) and an inhibitory agent, somatostatin.  Dopaminergic, adrenergic and serotoninergic neuroendocrine pathways also play an important role in the control of hGH secretion.  Excitatory stimuli of hGH secretion include hypoglycemia, exercise, fasting, meals with a high protein content, deep sleep, stress, glucagon, L Dopa, amino acids, etc.  Inhibitory stimuli include glucose, cortisol, hGH and free fatty acids.  Because of its short plasma half life (±25 minutes) and of the frequent excitatory or inhibitory stimuli, hGH displays frequent and large variations of concentration in serum.
One of the main physiological functions of hGH is to act on the liver and other tissues to produce Somatomedins, which in turn induce growth by direct action on target tissues.  In contrast to hGH, the concentration of somatomedin in serum is kept stable by virtue of being largely bound to circulating plasma proteins.
Growth retardation
hGH hyposecretion is one of the various causes of small stature in children.  Serum hGH measurement with a highly sensitive assay, especially following a provocative stimulus (absence of response), is an important way to establish this diagnosis because this group of patients can be treated by administration of hGH.
Hypopituitarism
Serum hGH measurement is also an index of pituitary function when hypopituitarism (either idiopathic or due to tumour and surgery) is suspected.
Gigantism and acromegaly
Serum hGH measurement, especially following a provocative inhibitory test (absence of response), is an important way to establish the diagnosis of hGH hypersecretion due to acidophilic pituitary tumour.  This results in gigantism in children and acromegaly in *****s.  Both of these disorders may be treated by surgery or radiation.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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