Ferritin

产品名称：Ferritin IRMA
产    地：Demeditec
产品货号：DE34100
产品规格：100 Tests
产品说明：
Special remarks:
Introduction
Ferritin is the main storage protein for iron  (Mw:450000) containing  protein shell  and a crystalline core iron oxide and phosphate. Low serum ferritin level is a useful diagnostic marker for iron-deficiency anemia. High ferritin levels may indicate iron overload in the case of hemochromatosis.  Elevated serum ferritin levels may also be  observed in acute and chronic liver disease.
Principle of method
The technology uses two high affinity monoclonal antibodies in an immuno-radiometric assay (IRMA) system. The 125I  labelled signal-antibody binds to an epitope of the ferritin molecule, which is different from that recognised by the unlabelled capture-antibody. The two antibodies react simul­taneously with the antigen present in standards or samples which leads to the formation of a capture antibody - antigen - signal antibody complex, also referred to as a “sandwich”. During a 2-hours incubation period with continuous agitation immuno-complex is immobilized on the reactive surface of test tubes. Reaction mixture is then discarded, test tubes are washed exhaustively, and the radioactivity is measured in a gamma counter. The concentration of antigen is directly proportional to the radio­activity measured in test tubes. By constructing a calib­ration curve plotting binding values against a series of standards containing known amount of ferritin, the unknown concentration of ferritin in patient samples can be determined.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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